Practical Value of Food Pathogen Traceability through Building a Whole-Genome Sequencing Network and Database

J Clin Microbiol. 2016 Aug;54(8):1975-83. doi: 10.1128/JCM.00081-16. Epub 2016 Mar 23.

Abstract

The FDA has created a United States-based open-source whole-genome sequencing network of state, federal, international, and commercial partners. The GenomeTrakr network represents a first-of-its-kind distributed genomic food shield for characterizing and tracing foodborne outbreak pathogens back to their sources. The GenomeTrakr network is leading investigations of outbreaks of foodborne illnesses and compliance actions with more accurate and rapid recalls of contaminated foods as well as more effective monitoring of preventive controls for food manufacturing environments. An expanded network would serve to provide an international rapid surveillance system for pathogen traceback, which is critical to support an effective public health response to bacterial outbreaks.

Publication types

  • Review
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Disease Outbreaks*
  • Food Microbiology / methods*
  • Food Safety / methods*
  • Foodborne Diseases / epidemiology*
  • Foodborne Diseases / prevention & control*
  • Genomics / methods*
  • Humans
  • United States / epidemiology

Grants and funding

This work was supported by internal research funding from the U.S. FDA, Center for Food Safety and Applied Nutrition