Prevalence of metabolic syndrome in non-diabetic, pregnant Angolan women according to four diagnostic criteria and its effects on adverse perinatal outcomes

Hamilton Dos Prazeres Tavares; Débora Cristina Damasceno Meirelles Dos Santos; Joelcio Francisco Abbade; Carlos Antonio Negrato; Paulo Adão de Campos; Iracema Mattos Paranhos Calderon; Marilza Vieira Cunha Rudge

doi:10.1186/s13098-016-0139-3

Prevalence of metabolic syndrome in non-diabetic, pregnant Angolan women according to four diagnostic criteria and its effects on adverse perinatal outcomes

Diabetol Metab Syndr. 2016 Mar 22:8:27. doi: 10.1186/s13098-016-0139-3. eCollection 2016.

Authors

Hamilton Dos Prazeres Tavares¹, Débora Cristina Damasceno Meirelles Dos Santos¹, Joelcio Francisco Abbade¹, Carlos Antonio Negrato¹, Paulo Adão de Campos², Iracema Mattos Paranhos Calderon¹, Marilza Vieira Cunha Rudge¹

Affiliations

¹ Department of Gynecology and Obstetrics, Botucatu Medical School, UNESP-Univ Estadual Paulista, Botucatu, São Paulo Brazil.
² Department of Gynecology and Obstetrics, Medical School, University Agostinho Neto (UAN), Luanda, Angola.

Abstract

Background: Metabolic syndrome (MetS) is a cluster of risk factors for type 2 diabetes (Type2 DM) and cardiovascular diseases (CVD), and its prevalence varies based on region, population, and sex. Newborns of women with MetS have a greater risk of adverse perinatal outcomes. This study explores the prevalence of metabolic syndrome in non-diabetic, pregnant Angolan women and the adverse perinatal outcomes associated with it.

Methods: This cross-sectional study collected the demographic, anthropometric and clinical data of 675 pregnant women in the maternity ward of General Hospital in Huambo, Angola. Metabolic syndrome was defined using four criteria: the third report of the National Cholesterol Education Program Adult Treatment Panel (ATPIII), the Joint Interim Statement (JIS), and definitions by both Bartha et al. and Chatzi et al.

Results: The crude prevalence of metabolic syndrome was 36.6 % based on the JIS definition, 29.2 % based on NCEP ATPIII, 12.6 % based on Chatzi et al. and 1.8 % based on Bartha et al. In general, the prevalence of adverse perinatal outcomes was 14.1 %.

Conclusions: There was a high prevalence of metabolic syndrome, depending on the criteria used, and thus a great need to harmonize the criteria and cutoff points. Perinatal adverse outcomes were higher in pregnant women with metabolic syndrome.

Keywords: Angola; Metabolic syndrome; Pregnancy perinatal outcome; Prevalence.