The incidence of infants with rotavirus enteritis combined with lactose intolerance

Pak J Pharm Sci. 2016 Jan;29(1 Suppl):321-3.

Abstract

This study was to research the incidence of infants with rotavirus enteritis combined with lactose intolerance and the clinical effect of low lactose milk powder for infantile rotavirus enteritis with lactose intolerance. The control groups were 126 cases of infants with diarrhea randomly collected from our hospital at the same period, which their rotavirus detection was negative. The observation group was 185 cases of infants with rotavirus, which was tested to be positive. Through the urine galactose determination, 62 cases of the control group were positive and 124 cases of the observation group were positive. Then 124 cases of infants with rotavirus combined with lactose intolerance were randomly divided into two groups. 60 cases in the control group were given rehydration, correction of acidosis, oral smecta, Intestinal probiotics and other conventional treatment, then continued to the original feeding method. While, 64 cases in the treatment group, on the basis of routine treatment, applied the low lactose milk feeding. To observe the total effective rate for the two groups. The incidence of lactose intolerance in children with rotavirus enteritis (67.03%) was significantly higher than that of children with diarrhea (49.2%), which was tested to be negative. And the difference was statistically significant (p<0.5). In the aspect of reducing the frequency of diarrhea, and diarrhea stool forming time, the treatment group has the obvious superiority. The total effective rate was 95.4% for treatment group, which was higher than that in the control group (76.7%), the difference was statistically significant (P<0.05).

Conclusion: Infants with rotavirus enteritis was easier to merge with lactose intolerance. The low lactose milk powder could improve the therapeutic effectively and could reduce the duration of disease, and restored to normal diet for 2 weeks feeding time.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Acidosis, Lactic / diet therapy
  • China / epidemiology
  • Dairy Products
  • Diarrhea / epidemiology
  • Diarrhea / etiology
  • Enteritis / diet therapy*
  • Enteritis / epidemiology*
  • Enteritis / etiology
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Lactose Intolerance / complications
  • Lactose Intolerance / diet therapy*
  • Lactose Intolerance / epidemiology*
  • Male
  • Probiotics / therapeutic use
  • Rotavirus Infections / complications
  • Rotavirus Infections / diet therapy*
  • Rotavirus Infections / epidemiology*
  • Treatment Outcome