[Klatskin tumor - a case report]

Pol Merkur Lekarski. 2016 Feb;40(236):107-9.
[Article in Polish]

Abstract

Cholangiocarcinoma (CCA) is the second most frequent liver malignancy, responsible for 10-15% primary liver cancers. This tumor is difficult to diagnose and characterized by high mortality rate. Extrahepatic CCA is a specific type known as Klatskin tumor.

A case report: The patient was admitted to the Clinic of Internal Medicine and Gastroenterology with intrahepatic cholestasis. Imaging revealed Bismuth type IV hilum tumor. Due to rare occurrence of this malignancy the patient was directed to the tertiary center. During surgical exploration radical treatment was abandoned as a result of tumor's advanced stadium. Histology evaluation revealed infiltrating adenocarcinoma. ERCP and biliary duct stenting was performed. The patient was qualified for paliative chemotherapy according to gemcytabine+cisplatine protocol (d1, d15 every 28 days). Posttreatment follow-up revealed total remission of the tumor.

Keywords: Klatskin tumor; biliary duct cancer; palliative therapies.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bile Duct Neoplasms / diagnosis
  • Bile Duct Neoplasms / drug therapy
  • Bile Duct Neoplasms / surgery
  • Bile Duct Neoplasms / therapy*
  • Bile Ducts, Extrahepatic*
  • Cisplatin / therapeutic use
  • Deoxycytidine / analogs & derivatives
  • Deoxycytidine / therapeutic use
  • Gemcitabine
  • Humans
  • Klatskin Tumor / diagnosis
  • Klatskin Tumor / drug therapy
  • Klatskin Tumor / surgery
  • Klatskin Tumor / therapy*
  • Male
  • Middle Aged
  • Remission Induction
  • Stents

Substances

  • Deoxycytidine
  • Cisplatin
  • Gemcitabine