Bartonella henselae infection presenting with a picture of adult-onset Still's disease

Int J Infect Dis. 2016 May:46:61-3. doi: 10.1016/j.ijid.2016.03.014. Epub 2016 Mar 18.

Abstract

We report a patient with a clinical picture of suggestive for adult-onset Still's Disease (ASOD) due to Bartonella infection. A 42-year-old immunocompetent man was admitted with fever, rash, arthralgia and sore throat. As his clinical picture suggested ASOD except unusual skin manifestation, we treated him on steroid and ibuprofen. His fever and constitutional symptoms responded immediately within 24hrs of commencing therapy, yet rash and leukocytosis remained. Meanwhile, Bartonella infection was proved by culture of bone marrow. Minocyclin treatment started combined with hydroxychloroquine sulfate and the patient discharged with overall improvement.

Keywords: Adult-Onset Still's disease; Autoimmune; Bartonella henselae; Bartonellosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bartonella Infections / drug therapy
  • Bartonella Infections / immunology
  • Bartonella Infections / microbiology*
  • Bartonella henselae / drug effects
  • Bartonella henselae / genetics
  • Bartonella henselae / isolation & purification
  • Bartonella henselae / physiology*
  • Female
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Male
  • Still's Disease, Adult-Onset / drug therapy
  • Still's Disease, Adult-Onset / immunology
  • Still's Disease, Adult-Onset / microbiology*

Substances

  • Hydroxychloroquine