Integrated profiling methods for identifying the targets of bioactive compounds: MorphoBase and ChemProteoBase

Nat Prod Rep. 2016 May 4;33(5):621-5. doi: 10.1039/c5np00106d.

Abstract

Covering: up to the end of 2015.Many useful compounds from natural products have been discovered through phenotype-based screening. However, the target identification process for compounds is laborious and time-consuming. With the development of new equipment and methodologies for biological analyses, a variety of profiling methods that utilize large sets of experimental data have been established. Here, we highlight the utility of our identification approaches, MorphoBase and ChemProteoBase.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biological Products / chemistry
  • Biological Products / pharmacology*
  • Drug Discovery*
  • Molecular Structure

Substances

  • Biological Products