Recognition of Mg²⁺ by a new fluorescent "turn-on" chemosensor based on pyridyl-hydrazono-coumarin

Jessica Orrego-Hernández; Nelson Nuñez-Dallos; Jaime Portilla

doi:10.1016/j.talanta.2016.02.020

Recognition of Mg²⁺ by a new fluorescent "turn-on" chemosensor based on pyridyl-hydrazono-coumarin

Talanta. 2016 May 15:152:432-7. doi: 10.1016/j.talanta.2016.02.020. Epub 2016 Feb 10.

Authors

Jessica Orrego-Hernández¹, Nelson Nuñez-Dallos¹, Jaime Portilla²

Affiliations

¹ Bioorganic Compounds Research Group, Department of Chemistry, Universidad de los Andes, Carrera 1 No. 18A 10, Bogotá, Colombia.
² Bioorganic Compounds Research Group, Department of Chemistry, Universidad de los Andes, Carrera 1 No. 18A 10, Bogotá, Colombia. Electronic address: jportill@uniandes.edu.co.

PMID: 26992539
DOI: 10.1016/j.talanta.2016.02.020

Abstract

A new fluoroionophore PyHC bearing 2-pyridylhydrazone and 7-hydroxycoumarin moieties for selective detection of Mg(2+) was synthesized and characterized. This chemosensor exhibited "turn-on" fluorescence behavior and was sensitive to Mg(2+) concentrations as low as 105 nmol L(-1) in ethanol-water solution. Detailed spectroscopic studies revealed the binding mode of a 1:1 complex between PyHC and Mg(2+) that leads to a fluorescence enhancement.

Keywords: Chemosensor; Fluorescence; Mg(2+); Pyridyl-hydrazono-coumarin; Schiff base.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Coumarins / chemistry*
Ethanol / chemistry
Fluorescent Dyes / chemistry*
Hydrazones / chemistry*
Limit of Detection
Magnesium / analysis*
Magnesium / chemistry*
Schiff Bases / chemistry
Spectrometry, Fluorescence
Spectrophotometry, Ultraviolet
Water / chemistry

Substances

7-hydroxy-4-methyl-8-((2-(pyridin-2-yl)hydrazono)methyl)-2H-chromen-2-one
Coumarins
Fluorescent Dyes
Hydrazones
Schiff Bases
Water
Ethanol
Magnesium