Highly selective and sensitive fluorescent probe for the detection of nitrite

Talanta. 2016 May 15:152:155-61. doi: 10.1016/j.talanta.2016.01.059. Epub 2016 Jan 29.

Abstract

A simple and reliable fluorescent nitrite (NO2(-)) probe, 2-(1H-phenanthro[9,10-d] imidazol-2-yl)aniline (PA), was rationally developed based on a novel NO2(-)-mediated diazozation and subsequent cyclization. The new sensing mechanism of the probe was confirmed by using NMR, IR spectra, control experiments and DFT calculations. The synthesized probe showed low pH dependence, fast and highly selective fluorescence response to NO2(-) over other species. Under the optimized conditions, the linear response of the probe toward NO2(-) was in the range of 0.1-10 μM with a low detection limit of 4.3×10(-8) M. Moreover, PA was successfully applied for the determination of NO2(-) in environmental samples and food products.

Keywords: Fluorescent probe; Highly selective response; Nitrite.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aniline Compounds / chemical synthesis
  • Aniline Compounds / chemistry*
  • Electron Transport
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • Food Analysis
  • Hydrogen-Ion Concentration
  • Limit of Detection*
  • Models, Molecular
  • Molecular Conformation
  • Nitrites / analysis*
  • Nitrites / chemistry*
  • Solvents / chemistry
  • Spectrometry, Fluorescence
  • Time Factors
  • Water / chemistry

Substances

  • Aniline Compounds
  • Fluorescent Dyes
  • Nitrites
  • Solvents
  • Water
  • aniline