The synergistic effect of NADPH and NADH on P450 function in processing premutagens

Pharmacol Res. 1989 Nov-Dec:21 Suppl 1:129-30. doi: 10.1016/s1043-6618(89)80085-4.
No abstract available

MeSH terms

  • Animals
  • Biotransformation / drug effects
  • Cytochrome P-450 Enzyme System / metabolism*
  • Drug Synergism
  • In Vitro Techniques
  • Mice
  • Mutagens / pharmacokinetics*
  • NAD / pharmacology*
  • NADP / pharmacology*
  • Phenobarbital / pharmacology
  • Saccharomyces cerevisiae / genetics

Substances

  • Mutagens
  • NAD
  • NADP
  • Cytochrome P-450 Enzyme System
  • Phenobarbital