Visible light-photocatalysed carbazole synthesis via a formal (4+2) cycloaddition of indole-derived bromides and alkynes

Chem Commun (Camb). 2016 Apr 14;52(29):5128-31. doi: 10.1039/c5cc10542k. Epub 2016 Mar 18.

Abstract

We successfully developed an unprecedented route to carbazole synthesis through a visible light-photocatalysed formal (4+2) cycloaddition of indole-derived bromides and alkynes. This novel protocol features extremely mild conditions, a broad substrate scope and high reaction efficiency.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemical synthesis
  • Alkynes / chemistry*
  • Bromides / chemical synthesis
  • Bromides / chemistry*
  • Carbazoles / chemical synthesis*
  • Carbazoles / chemistry
  • Catalysis
  • Cycloaddition Reaction
  • Indoles / chemical synthesis
  • Indoles / chemistry*
  • Light

Substances

  • Alkynes
  • Bromides
  • Carbazoles
  • Indoles
  • carbazole
  • indole