The wound/burn guidelines - 3: Guidelines for the diagnosis and treatment for diabetic ulcer/gangrene

Taiki Isei; Masatoshi Abe; Takeshi Nakanishi; Koma Matsuo; Osamu Yamasaki; Yoshihide Asano; Takayuki Ishii; Takaaki Ito; Yuji Inoue; Shinichi Imafuku; Ryokichi Irisawa; Masaki Ohtsuka; Mikio Ohtsuka; Fumihide Ogawa; Takafumi Kadono; Masanari Kodera; Tamihiro Kawakami; Masakazu Kawaguchi; Ryuichi Kukino; Takeshi Kono; Keisuke Sakai; Masakazu Takahara; Miki Tanioka; Yasuhiro Nakamura; Akira Hashimoto; Minoru Hasegawa; Masahiro Hayashi; Manabu Fujimoto; Hiroshi Fujiwara; Takeo Maekawa; Naoki Madokoro; Yuichiro Yoshino; Andres Le Pavoux; Takao Tachibana; Hironobu Ihn; Wound/Burn Guidelines Committee

doi:10.1111/1346-8138.13285

The wound/burn guidelines - 3: Guidelines for the diagnosis and treatment for diabetic ulcer/gangrene

J Dermatol. 2016 Jun;43(6):591-619. doi: 10.1111/1346-8138.13285. Epub 2016 Mar 12.

Authors

Taiki Isei¹, Masatoshi Abe², Takeshi Nakanishi³, Koma Matsuo⁴, Osamu Yamasaki⁵, Yoshihide Asano⁶, Takayuki Ishii⁷, Takaaki Ito⁸, Yuji Inoue⁹, Shinichi Imafuku¹⁰, Ryokichi Irisawa¹¹, Masaki Ohtsuka⁵, Mikio Ohtsuka¹², Fumihide Ogawa¹³, Takafumi Kadono⁶, Masanari Kodera¹⁴, Tamihiro Kawakami¹⁵, Masakazu Kawaguchi¹⁶, Ryuichi Kukino¹⁷, Takeshi Kono¹⁸, Keisuke Sakai¹⁹, Masakazu Takahara²⁰, Miki Tanioka²¹, Yasuhiro Nakamura²², Akira Hashimoto²³, Minoru Hasegawa⁷, Masahiro Hayashi¹⁶, Manabu Fujimoto⁷, Hiroshi Fujiwara²⁴, Takeo Maekawa²⁵, Naoki Madokoro²⁶, Yuichiro Yoshino²⁷, Andres Le Pavoux²⁸, Takao Tachibana²⁹, Hironobu Ihn⁹; Wound/Burn Guidelines Committee

Affiliations

¹ Department of Dermatology, Kansai Medical University, Osaka, Japan.
² Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan.
³ Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan.
⁴ Department of Dermatology, The Jikei University School of Medicine, Tokyo, Japan.
⁵ Department of Dermatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
⁶ Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
⁷ Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Ishikawa, Japan.
⁸ Department of Dermatology, Hyogo College of Medicine, Hyogo, Japan.
⁹ Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
¹⁰ Department of Dermatology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
¹¹ Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
¹² Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
¹³ Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
¹⁴ Department of Dermatology, Japan Community Health Care Organization Chukyo Hospital, Aichi, Japan.
¹⁵ Department of Dermatology, St. Marianna University School of Medicine, Kanagawa, Japan.
¹⁶ Department of Dermatology, Yamagata University Faculty of Medicine, Yamagata, Japan.
¹⁷ Department of Dermatology, NTT Medical Center, Tokyo, Japan.
¹⁸ Department of Dermatology, Nippon Medical School, Tokyo, Japan.
¹⁹ Intensive Care Unit, Kumamoto University Hospital, Kumamoto, Japan.
²⁰ Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
²¹ Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
²² Department of Dermatology, University of Tsukuba, Ibaraki, Japan.
²³ Department of Dermatology, Tohoku University Graduate School of Medicine, Miyagi, Japan.
²⁴ Department of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
²⁵ Department of Dermatology, Jichi Medical University, Tochigi, Japan.
²⁶ Department of Dermatology, Mazda Hospital, Hiroshima, Japan.
²⁷ Department of Dermatology, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan.
²⁸ Ichige Dermatology Clinic, Ibaraki, Japan.
²⁹ Department of Dermatology, Osaka Red Cross Hospital, Osaka, Japan.

PMID: 26972937
DOI: 10.1111/1346-8138.13285

Abstract

We aimed to prepare guidelines for the management of diabetic ulcer/gangrene with emphasis on the diagnosis and treatment of skin symptoms. They serve as a tool to improve the quality of the diagnosis and treatment in each patient and, further, to improve the level of the care for diabetic ulcer in Japan by systematically presenting evidence-based recommendations for clinical judgments by incorporating various viewpoints.

Keywords: diabetic complications; diabetic gangrene; diabetic patients; diabetic skin ulcer; podiatrist.

Publication types

Practice Guideline

MeSH terms

Aldehyde Reductase / antagonists & inhibitors
Anti-Bacterial Agents / administration & dosage
Blood Component Removal
Debridement
Diabetic Foot / complications
Diabetic Foot / diagnosis
Diabetic Foot / therapy*
Diabetic Nephropathies / diagnosis
Gangrene / diagnosis
Gangrene / etiology
Gangrene / therapy*
Humans
Hyperbaric Oxygenation
Ischemia / diagnosis
Ischemia / etiology
Negative-Pressure Wound Therapy
Orthotic Devices
Osteomyelitis / diagnostic imaging
Osteomyelitis / drug therapy
Osteomyelitis / etiology
Renal Dialysis / adverse effects
Wound Healing

Substances

Anti-Bacterial Agents
Aldehyde Reductase