Current views on the diagnosis and management of hypokalaemia in children

Acta Paediatr. 2016 Jul;105(7):762-72. doi: 10.1111/apa.13398. Epub 2016 Apr 20.

Abstract

Hypokalaemia is a common electrolyte disorder in children, caused by decreased potassium intake, increased gastrointestinal and urinary losses or transcellular shift. Patients with severe hypokalaemia may suffer from symptoms such as life-threatening cardiac arrhythmias. The aim of our study was to review the aetiology of hypokalaemia, suggest a diagnostic algorithm and discuss the management of patients with various aetiologies of hypokalaemia.

Conclusion: Understanding the pathophysiology of hypokalaemic states, along with a detailed medical history, physical examination and specific laboratory tests are required for proper diagnosis and appropriate treatment.

Keywords: Bartter syndrome; Children; Gitelman syndrome; Hypokalaemia; Steroidogenesis disorders.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Diseases / complications
  • Child
  • Disease Management
  • Genetic Diseases, Inborn / complications
  • Humans
  • Hypokalemia / diagnosis
  • Hypokalemia / etiology*
  • Hypokalemia / therapy