Nutritional intervention with hypocaloric diet for weight control in children and adolescents with Prader-Willi Syndrome

Eat Behav. 2016 Apr:21:189-92. doi: 10.1016/j.eatbeh.2016.03.008. Epub 2016 Mar 5.

Abstract

Prader-Willi Syndrome (PWS) is a genetic disorder caused by the lack of expression of paternal alleles in the proximal region of the long arm of chromosome 15. Low inhibitory control and hyperphagia are two of the most severe neurobehavioral symptoms of the syndrome. The aim of the present study was to assess the efficiency of nutritional training program with the use hypocaloric diet for weight control in a group of five children and adolescents with PWS. The intervention program consisted of 10 sessions for parents' orientation during 8months. Patients had their anthropometric measures assessed (weight, height and body mass index - BMI). The main results indicate weight maintenance, height increase, and BMI decrease after intervention. These results were considered indicators of the program's efficiency.

Keywords: Nutritional intervention; Obesity; Prader–Willi Syndrome.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Body Mass Index
  • Body Weight
  • Child
  • Diet, Reducing* / economics
  • Feeding Behavior
  • Female
  • Humans
  • Hyperphagia / complications
  • Hyperphagia / diet therapy
  • Hyperphagia / prevention & control
  • Male
  • Obesity / complications*
  • Obesity / diet therapy*
  • Obesity / prevention & control
  • Prader-Willi Syndrome / complications*