Soft corals belonging to the genus Cespitularia have been well recognized as a rich source of bioactive secondary metabolites especially diterpenoids. This review furnishes an overview of all naturally isolated compounds from Cespitularia genus as, diterpenoids, nitrogen-containing diterpenes, sesquiterpenoids and steroids as well as biological activities of these species. Cespitularia species have been studied for their anticancer, immunomodulatory, antiviral, antimicrobial, and anti-inflammatory activities. This work is the first review published on this topic.
Keywords: Anti-inflammatory; Anticancer; Cespitularia; Steroids; Terpenoids.