Background: There is a paucity of data regarding the role of side branch (SB) predilation during the provisional stenting of bifurcation lesions.
Objectives: The present study aimed to assess the effects of SB predilation on the outcomes of true bifurcation interventions.
Patients and methods: Sixty patients with true bifurcation lesions according to the Medina classification were included in the study and randomly assigned to receive SB predilation before stenting the main branch (n = 30) or no predilation as the control group (n = 30).
Results: There was a trend toward the higher occurrence of dissection in the predilated ostial lesions of the SB compared to the non-predilated group (16.7% vs. 0, P = 0.07). Performance of the SB predilation was not associated with improved flow of the SB or fewer degrees of ostial stenosis after stenting the main branch, the need to rewire, rewiring time, or the rate of use of the final kissing balloon dilation and double stents procedures.
Conclusions: Routine predilation of the SB in provisional stenting of true bifurcation lesions seems to be ineffective and might be associated with some undesirable consequences. Still, there are some complex ostial lesions of the SB which could benefit from predilation.
Keywords: Coronary Artery Disease; Coronary Artery Stenting; Percutaneous Coronary Intervention.