Drug-Drug Interaction Extraction via Convolutional Neural Networks

Comput Math Methods Med. 2016:2016:6918381. doi: 10.1155/2016/6918381. Epub 2016 Jan 31.

Abstract

Drug-drug interaction (DDI) extraction as a typical relation extraction task in natural language processing (NLP) has always attracted great attention. Most state-of-the-art DDI extraction systems are based on support vector machines (SVM) with a large number of manually defined features. Recently, convolutional neural networks (CNN), a robust machine learning method which almost does not need manually defined features, has exhibited great potential for many NLP tasks. It is worth employing CNN for DDI extraction, which has never been investigated. We proposed a CNN-based method for DDI extraction. Experiments conducted on the 2013 DDIExtraction challenge corpus demonstrate that CNN is a good choice for DDI extraction. The CNN-based DDI extraction method achieves an F-score of 69.75%, which outperforms the existing best performing method by 2.75%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Data Mining / methods
  • Drug Interactions*
  • Humans
  • Machine Learning
  • Models, Statistical
  • Natural Language Processing
  • Neural Networks, Computer*
  • Pattern Recognition, Automated / methods
  • Regression Analysis
  • Semantics
  • Support Vector Machine