Feedback regulation of biological networks: Examples relevant to signalling pathways and resistance to pharmacological interceptors

Semin Cell Dev Biol. 2016 Feb:50:83-4. doi: 10.1016/j.semcdb.2016.02.016.

Authors

Yosef Yarden¹, Deric L Wheeler²

Affiliations

¹ Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address: yosef.yarden@weizmann.ac.il.
² Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

PMID: 26940064
DOI: 10.1016/j.semcdb.2016.02.016

No abstract available

Publication types

Editorial
Introductory Journal Article

MeSH terms

Animals
Antineoplastic Agents / pharmacology
Dual Specificity Phosphatase 1 / metabolism
Feedback, Physiological*
Humans
Pharmaceutical Preparations / metabolism*
Protein Kinases / metabolism
Receptors, G-Protein-Coupled / metabolism
Signal Transduction*

Substances

Antineoplastic Agents
Pharmaceutical Preparations
Receptors, G-Protein-Coupled
Protein Kinases
Dual Specificity Phosphatase 1