Food-derived immunomodulatory peptides

J Sci Food Agric. 2016 Aug;96(11):3631-41. doi: 10.1002/jsfa.7697. Epub 2016 Apr 15.

Abstract

Food proteins contain specific amino acid sequences within their structures that may positively impact bodily functions and have multiple immunomodulatory effects. The functional properties of these specific sequences, also referred to as bioactive peptides, are revealed only after the degradation of native proteins during digestion processes. Currently, milk proteins have been the most explored source of bioactive peptides, which presents an interesting opportunity for the dairy industry. However, plant- and animal-derived proteins have also been shown to be important sources of bioactive peptides. This review summarizes the in vitro and in vivo evidence of the role of various food proteins as sources of immunomodulatory peptides and discusses the possible pathways involving these properties. © 2016 Society of Chemical Industry.

Keywords: food proteins; immunomodulatory peptides.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Diet*
  • Dietary Proteins / pharmacology*
  • Humans
  • Immune System / drug effects*
  • Milk Proteins / pharmacology
  • Peptides / pharmacology*
  • Plant Proteins / pharmacology

Substances

  • Dietary Proteins
  • Milk Proteins
  • Peptides
  • Plant Proteins