Routine Screening for Callosal Dysgenesis in the Second Trimester Is Achievable With Intensive Training

J Ultrasound Med. 2016 Apr;35(4):717-22. doi: 10.7863/ultra.15.05069. Epub 2016 Mar 1.

Abstract

Objectives: The purpose of this study was to determine whether routine direct visualization of the corpus callosum is achievable during second-trimester sonography when performed by a large group of sonographers in a general second-trimester sonographic screening program. The secondary aim was to determine the time taken to obtain a sagittal corpus callosum image.

Methods: We conducted a retrospective cohort study of visualization of the corpus callosum before and after intensive training. Images from 150 consecutive second-trimester scans were reviewed before and after training to evaluate the image quality of the corpus callosum.

Results: A total of 300 cases were evaluated before and after training. There was a significant increase in the rate of complete visualization of the corpus callosum after intensive training (P < .0001). Before training 35 of 150 cases (23%) had complete visualization of the corpus callosum versus 107 of 150 (71%) after training. The mean time to perform the corpus callosum views was 53.4 seconds before training compared to 56.2 seconds after training.

Conclusions: Assessing the corpus callosum in the sagittal view is difficult and requires appropriate training and patience; however, this view is feasible without adding substantial time to the examination and provides additional information during a routine second-trimester morphologic scan.

Keywords: callosal dysgenesis; corpus callosum; obstetric ultrasound; screening; sonography; training.

Publication types

  • Multicenter Study

MeSH terms

  • Agenesis of Corpus Callosum / diagnostic imaging
  • Agenesis of Corpus Callosum / epidemiology*
  • Australia / epidemiology
  • Clinical Competence / statistics & numerical data*
  • Cohort Studies
  • Female
  • Humans
  • Inservice Training / statistics & numerical data*
  • Male
  • Mass Screening / statistics & numerical data*
  • Observer Variation
  • Pregnancy
  • Pregnancy Trimester, Second
  • Prevalence
  • Reproducibility of Results
  • Risk Factors
  • Sensitivity and Specificity
  • Ultrasonography, Prenatal / statistics & numerical data*