New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides

Gilles Hanquet; Xavier Salom-Roig; Steve Lanners

doi:10.2533/chimia.2016.20

New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides

Chimia (Aarau). 2016;70(1-2):20-8. doi: 10.2533/chimia.2016.20.

Authors

Gilles Hanquet¹, Xavier Salom-Roig², Steve Lanners³

Affiliations

¹ Université de Strasbourg UMR CNRS 7509, ECPM 25 rue Becquerel, 67087 Strasbourg, France. ghanquet@unistra.fr.
² Institut de Biomolécules Max Mousseron (IBMM) UMR 5247, CNRS-Université de Montpellier Place Eugène Bataillon, 34095 Montpellier, France. salom-roig@univ-montp2.fr.
³ University of Namur Department of Chemistry and Namur Medicine & Drug Innovation Center (NAMEDIC) 61 rue de Bruxelles, 5000 Namur, Belgium. steve.lanners@unamur.be.

PMID: 26931213
DOI: 10.2533/chimia.2016.20

Abstract

After a brief account of the biological properties of pamamycins, this review highlights the latest developments on the total synthesis and the biosynthesis of these macrodiolides.

Publication types

Review

MeSH terms

Anti-Bacterial Agents / chemical synthesis*
Anti-Bacterial Agents / pharmacology*
Indicators and Reagents
Macrolides / chemical synthesis*
Macrolides / pharmacology*

Substances

Anti-Bacterial Agents
Indicators and Reagents
Macrolides
pamamycin