Clinical analysis of 26 patients with histologically proven placental chorioangiomas

Eur J Obstet Gynecol Reprod Biol. 2016 Apr:199:156-63. doi: 10.1016/j.ejogrb.2015.12.009. Epub 2015 Dec 30.

Abstract

Objectives: The purpose of this study was to evaluate the clinical characteristics, imaging features, pregnancy complications, prenatal management of patients with placenta chorioangioma.

Methods: This was a retrospective study of 26 cases with histologically proven placenta chorioangima, in which the natural history, pregnancy complications, and clinical characteristics including ultrasonography were evaluated.

Results: Twelve of the twenty-six cases had a wide range of maternal-fetal complications including polyhydramnios (7), fetal growth restriction (3), fetal distress (2), pre-eclampsia (3), fetal anemia-thrombocytopenia (2), congestive heart failure (1) and fetal abnormality (1).

Conclusions: Placenta chorioangioma was associated with series of pregnancy complications such as polyhytramnios, premature delivery, maternal pre-eclampsia, fetal growth restriction, fetal distress, even fetal anemia and cardiomegaly. With regular prenatal examination, necessary treatment, and timely delivery, the majority had a good pregnancy outcome.

Keywords: Follow-up; Placenta chorioangioma; Pregnancy complication; Prenatal diagnosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Hemangioma / diagnostic imaging
  • Hemangioma / pathology*
  • Humans
  • Placenta / diagnostic imaging
  • Placenta / pathology*
  • Placenta Diseases / diagnostic imaging
  • Placenta Diseases / pathology*
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnostic imaging
  • Pregnancy Complications, Neoplastic / pathology*
  • Pregnancy Outcome
  • Retrospective Studies
  • Ultrasonography, Prenatal