Stratification and Risk Reduction of Perioperative Acute Kidney Injury

Selma Ishag; Charuhas V Thakar

doi:10.1016/j.anclin.2015.10.009

Stratification and Risk Reduction of Perioperative Acute Kidney Injury

Anesthesiol Clin. 2016 Mar;34(1):89-99. doi: 10.1016/j.anclin.2015.10.009.

Authors

Selma Ishag¹, Charuhas V Thakar²

Affiliations

¹ Division of General Anesthesiology, Barnes-Jewish Hospital, Washington University, South Campus, Campus Box 8054, 660 South Euclid Avenue, St Louis, MO 63110-1093, USA. Electronic address: ishags@anest.wustl.edu.
² Division of Nephrology, Kidney CARE Program, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267, USA; Renal Section, Cincinnati VA Medical Center, 231 Albert Sabin Way, Cincinnati, OH 45267, USA.

PMID: 26927741
DOI: 10.1016/j.anclin.2015.10.009

Abstract

Perioperative acute kidney injury (AKI) is associated with an increased morbidity and mortality. The incidence of AKI varies depending on preoperative risk factors and the surgical setting. Preoperative risk stratification is critical for informed consent and perioperative planning. Perioperative renal protection strategies are potentially invaluable in the prevention of AKI. Current advances in the development of biomarkers may offer the opportunity for early diagnosis and the implementation of therapeutic strategies. Increased awareness and concerted efforts by all perioperative physicians are needed to provide an improved outcome for surgical patients.

Keywords: Acute kidney injury; Chronic kidney disease; Preoperative evaluation; Renal protection strategies.

Publication types

Review

MeSH terms

Acute Kidney Injury / complications
Acute Kidney Injury / epidemiology
Acute Kidney Injury / prevention & control*
Humans
Intraoperative Complications / prevention & control
Postoperative Complications / prevention & control
Preoperative Period
Risk Assessment / methods*
Risk Reduction Behavior*