Curcumin and Health

Molecules. 2016 Feb 25;21(3):264. doi: 10.3390/molecules21030264.

Abstract

Nowadays, there are some molecules that have shown over the years a high capacity to act against relevant pathologies such as cardiovascular disease, neurodegenerative disorders or cancer. This article provides a brief review about the origin, bioavailability and new research on curcumin and synthetized derivatives. It examines the beneficial effects on health, delving into aspects such as cancer, cardiovascular effects, metabolic syndrome, antioxidant capacity, anti-inflammatory properties, and neurological, liver and respiratory disorders. Thanks to all these activities, curcumin is positioned as an interesting nutraceutical. This is the reason why it has been subjected to several modifications in its structure and administration form that have permitted an increase in bioavailability and effectiveness against different diseases, decreasing the mortality and morbidity associated to these pathologies.

Keywords: ROS; anti-inflammatory; antioxidant; bioavailability; cancer; cardiovascular diseases; curcumin; liver disorders; lung diseases; natural compound.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / chemical synthesis
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / therapeutic use*
  • Antineoplastic Agents, Phytogenic / chemical synthesis
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / therapeutic use*
  • Antioxidants / chemical synthesis
  • Antioxidants / isolation & purification
  • Antioxidants / therapeutic use*
  • Biological Availability
  • Cardiotonic Agents / chemical synthesis
  • Cardiotonic Agents / isolation & purification
  • Cardiotonic Agents / therapeutic use*
  • Cardiovascular Diseases / drug therapy
  • Curcuma / chemistry*
  • Curcumin / chemical synthesis
  • Curcumin / isolation & purification
  • Curcumin / therapeutic use*
  • Humans
  • Inflammation
  • Neoplasms / drug therapy
  • Neurodegenerative Diseases / drug therapy
  • Neuroprotective Agents / chemical synthesis
  • Neuroprotective Agents / isolation & purification
  • Neuroprotective Agents / therapeutic use*
  • Plants, Medicinal

Substances

  • Anti-Inflammatory Agents
  • Antineoplastic Agents, Phytogenic
  • Antioxidants
  • Cardiotonic Agents
  • Neuroprotective Agents
  • Curcumin