Ultrathin MXene-Micropattern-Based Field-Effect Transistor for Probing Neural Activity

Abstract

A field-effect transistor (FET) based on ultrathin Ti3 C2 -MXene micropatterns is developed and utilized as a highly sensitive biosensor. The device is produced with the microcontact printing technique, making use of its unique advantages for easy fabrication. Using the MXene-FET device, label-free probing of small molecules in typical biological environments and fast detection of action potentials in primary neurons is demonstrated.

Keywords: MXenes biosensors; dopamine detection; field-effect transistors; micropatterning; neural engineering.