Catecholaminergic Polymorphic Ventricular Tachycardia

Marwan M Refaat; Sylvana Hassanieh; Melvin Scheinman

doi:10.1016/j.ccep.2015.10.035

Catecholaminergic Polymorphic Ventricular Tachycardia

Card Electrophysiol Clin. 2016 Mar;8(1):233-7. doi: 10.1016/j.ccep.2015.10.035.

Authors

Marwan M Refaat¹, Sylvana Hassanieh², Melvin Scheinman³

Affiliations

¹ Cardiology, Department of Internal Medicine, American University of Beirut Faculty of Medicine and Medical Center, PO Box 11-0236, Riad El-Solh, Beirut 1107 2020, Lebanon; Department of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address: mr48@aub.edu.lb.
² Department of Biochemistry and Molecular Genetics, American University of Beirut Medical Center, Beirut, Lebanon.
³ Division of Cardiology, Department of Medicine, University of California San Francisco Medical Center, San Francisco, CA, USA.

PMID: 26920200
DOI: 10.1016/j.ccep.2015.10.035

Abstract

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a challenging and serious disease with a high incidence of sudden cardiac deaths. Patients with CPVT should not be exposed to physical or emotional exertion that might induce ventricular tachycardia. This article presents a case with CPVT and discusses the clinical features of the disease, its genetic background, and the management of CPVT.

Keywords: Cardiac; Catecholaminergic; Polymorphic; Ventricular tachycardia.

Publication types

Case Reports
Review

MeSH terms

Adult
Electrocardiography
Female
Humans
Mutation
Ryanodine Receptor Calcium Release Channel / genetics
Syncope
Tachycardia, Ventricular*

Substances

Ryanodine Receptor Calcium Release Channel

Supplementary concepts

Polymorphic catecholergic ventricular tachycardia