Pediatric victims of AIDS virus infection continue to increase. The major source of transmission is by birth from an HIV-positive mother. Recognition is often difficult because of the varied and misleading signs and symptoms. Only a few studies describe oral manifestations in children and adolescents. The most common oral findings include candidiasis, parotid salivary gland enlargement and herpetic infections. Oral involvement may reflect early signs and symptoms of HIV-related immunosuppression.