Pediatric advanced life support (PALS) is the global standard of pediatric emergency medicine. It depends on the consensus of ILCOR which has been revised every 5 years by the experts worldwide. The concept of PALS is to treat the sick and injured children based on the systematic approach of the evaluation and classification in terms of the respiratory and circulatory status. On the other hand, point of care ultrasound (POCU) has been getting popular worldwide in the field of the emergency and critical care medicine. The PALS approach mainly depends on the physical examination which isn't enough for the decision making of the treatment. Then, POCU has come out as the adjunctive methods to compensate for the physical examination. This article outlines the concept of PALS and POCU.