Daptomycin for Children in Clinical Practice Experience

Pediatr Infect Dis J. 2016 Jun;35(6):639-41. doi: 10.1097/INF.0000000000001121.

Abstract

Data on daptomycin use in the pediatric setting are scanty. We conducted a multicenter, retrospective study on 46 children treated with intravenous daptomycin at a mean dosage of 7.0 mg/kg/d, for a median of 14 days. Three children had adverse events possibly related to daptomycin. The drug was overall well tolerated, even with prolonged treatment.

Publication types

  • Multicenter Study

MeSH terms

  • Administration, Intravenous
  • Adolescent
  • Anti-Bacterial Agents / administration & dosage*
  • Anti-Bacterial Agents / adverse effects
  • Bacterial Infections / drug therapy*
  • Child
  • Child, Preschool
  • Daptomycin / administration & dosage*
  • Daptomycin / adverse effects
  • Drug-Related Side Effects and Adverse Reactions / epidemiology
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents
  • Daptomycin