Ground-glass nodules (GGNs) was a special type of pulmonary nodules. With the progress of high resolution CT (HRCT), it achieved a higher positive rate and attracted much attention in recent years. For lacking characteristic symptoms, the early diagnosis of lung cancer was difficult even nowadays. However, it had been proved that GGNs was well associated with lung cancer in previous studies. Therefore, optimized managements of GGNs could help diagnosis and treatments of lung cancer at early stage. In this review, we summarized the definition, classification, imaging characteristics, growing history, molecular pathological features and suggested managements of GGNs.
磨玻璃结节(ground-glass nodules, GGNs)是肺结节中的特殊类型,随着高分辨薄层计算机断层扫描(high resolution computed tomography, HRCT)的应用,GGNs检出率逐年升高并受到日益广泛的关注。由于缺乏特征性临床症状,肺癌的早期诊断难度较大,而既往研究证实GGNs的出现常常提示与肺癌相关,因此加强筛查及管理有助于早期诊断及治疗肺癌。本文回顾既往相关研究,就GGNs的定义、分类、影像学特征、自然生长史、分子病理特征及诊治流程作一小结。.