AGTR1 has undergone natural selection in Euro-Asian populations in relation to ambient temperature that predisposes Chinese populations to essential hypertension

Int J Cardiol. 2016 Apr 15:209:278-80. doi: 10.1016/j.ijcard.2016.02.031. Epub 2016 Feb 5.

¹ Department of Biochemistry, School of Medicine, Ningbo University, Ningbo, China; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
² Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China; Laboratory for Genetics of Disease Susceptibility, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
³ State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China; Department of Preventive Medicine, School of Medicine, Ningbo University, Ningbo, China. Electronic address: xujin1@nbu.edu.cn.

No abstract available

Keywords: AGTR1; Ambient temperature; Genetic susceptibility; Hypertension; Natural selection; Renin–angiotensin–aldosterone system.

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