Laparoscopic Radiofrequency Ablation for Large Subcapsular Hepatic Hemangiomas: Technical and Clinical Outcomes

PLoS One. 2016 Feb 22;11(2):e0149755. doi: 10.1371/journal.pone.0149755. eCollection 2016.

Abstract

Objectives: The aim of this study was to evaluate the technical and clinical outcomes of using laparoscopic radiofrequency (RF) ablation for treating large subcapsular hepatic hemangiomas.

Methods: We retrospectively reviewed our sequential experience of treating 124 large subcapsular hepatic hemangiomas in 121 patients with laparoscopic RF ablation.

Results: The mean diameter of the 124 hemangiomas was 9.1 ± 3.2 cm (5.0-16.0 cm). RF ablation was performed successfully in all patients. There were 55 complications related to the ablation in 26 patients, including 5 of 69 (7.3%) patients with hemangioma <10 cm and 21 of 52 (40.4%) patients with hemangiomas ≥10 cm (P < 0.001). No injuries to abdominal viscera occurred in all the 121 patients. According to the Dindo-Clavien classification, all the complications were minor in 26 patients (Grade I). Out of 124 hepatic hemangiomas, 118 (95.2%) were completely ablated, including 70 of 72 (97.2%) lesions < 10 cm and 48 of 52 (92.3%) lesions ≥ 10 cm (P = 0.236).

Conclusion: Laparoscopic RF ablation therapy is a safe, feasible and effective procedure for large subcapsular hepatic hemangiomas, even in the hepatic hemangiomas ≥ 10 cm. Its use avoids thermal injury to the abdominal viscera.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Catheter Ablation*
  • Female
  • Follow-Up Studies
  • Hemangioma / surgery*
  • Humans
  • Laparoscopy*
  • Liver Neoplasms / surgery*
  • Male
  • Middle Aged
  • Retrospective Studies

Grants and funding

This study was supported by grants 320675007131 and 32067501207 from the Dr. Jieping Wu Medical Foundation, Clinical-Basic Medicine Cooperation Fund of Capital Medical University (1300171711), and the Program for Medical Key Discipline of Shijingshan District (20130001).