Does this patient have hypertensive encephalopathy?

J Am Soc Hypertens. 2016 May;10(5):399-403. doi: 10.1016/j.jash.2016.01.020. Epub 2016 Jan 29.

Abstract

A 63-year-old man was admitted to our hospital for further investigation and management of brain metastases. The patient was initially presented with a 4-day history of confusion. On the day of admission, the patient was confused, agitated, disorientated in place and time, and had visual disturbances. His blood pressure was repeatedly recorded high, with levels of systolic blood pressure between 170-210 mm Hg. A brain magnetic resonance imaging showed areas of high signal on T2 and fluid-attenuated inversion recovery images, located bilaterally in the white matter of the occipital regions and unilateral in the left frontal lobe, suggestive of posterior reversible encephalopathy syndrome. Aggressive treatment of hypertension resulted in complete resolution of the clinical and radiologic features of the syndrome.

Keywords: Hypertension; PRES; confusion; encephalopathy.

Publication types

  • Case Reports

MeSH terms

  • Amlodipine / administration & dosage
  • Amlodipine / therapeutic use
  • Antihypertensive Agents / administration & dosage
  • Antihypertensive Agents / adverse effects
  • Antihypertensive Agents / therapeutic use*
  • Biphenyl Compounds / administration & dosage
  • Biphenyl Compounds / adverse effects
  • Biphenyl Compounds / therapeutic use
  • Brain / diagnostic imaging*
  • Carbazoles / administration & dosage
  • Carbazoles / therapeutic use
  • Carvedilol
  • Computed Tomography Angiography
  • Confusion / etiology
  • Creatinine / blood
  • Electrocardiography
  • Glomerular Filtration Rate
  • Hallucinations / etiology
  • Headache / etiology
  • Heart / diagnostic imaging
  • Humans
  • Hydrochlorothiazide / administration & dosage
  • Hydrochlorothiazide / therapeutic use
  • Hypertension / complications*
  • Hypertension / drug therapy*
  • Hypertensive Encephalopathy / complications
  • Hypertensive Encephalopathy / diagnosis*
  • Irbesartan
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Propanolamines / administration & dosage
  • Propanolamines / therapeutic use
  • Renal Artery Obstruction / blood
  • Renal Artery Obstruction / chemically induced*
  • Spironolactone / administration & dosage
  • Spironolactone / therapeutic use
  • Tetrazoles / administration & dosage
  • Tetrazoles / adverse effects
  • Tetrazoles / therapeutic use
  • Ultrasonography

Substances

  • Antihypertensive Agents
  • Biphenyl Compounds
  • Carbazoles
  • Propanolamines
  • Tetrazoles
  • Hydrochlorothiazide
  • Carvedilol
  • Amlodipine
  • Spironolactone
  • Creatinine
  • Irbesartan