Visceral leishmaniasis after orthotopic liver transplantation: a rare cause of infection

Transpl Infect Dis. 2016 Apr;18(2):251-4. doi: 10.1111/tid.12511. Epub 2016 Mar 29.

Abstract

Visceral leishmaniasis (VL) was known as an opportunistic infection associated with immunosuppression, particularly related to human immunodeficiency virus infection and rarely to solid organ transplant recipients. We report a case of VL, 6 months after liver transplantation, in a patient who presented with febrile pancytopenia. The diagnosis was made by demonstration of amastigotes in smears from bone marrow. VL is a very rare infection in patients who undergo liver transplantation and, to our knowledge, this is the first case diagnosed in Portugal.

Keywords: post-transplant infection; solid organ transplantation; splenomegaly; visceral leishmaniasis.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use*
  • Antiprotozoal Agents / therapeutic use
  • Female
  • Humans
  • Immunocompromised Host
  • Leishmaniasis, Visceral / drug therapy*
  • Leishmaniasis, Visceral / etiology*
  • Liver Transplantation / adverse effects*
  • Middle Aged

Substances

  • Antiprotozoal Agents
  • liposomal amphotericin B
  • Amphotericin B