Reconstructive Endovascular Treatment of an Intracranial Infectious Aneurysm in Bacterial Meningitis: A Case Report and Review of Literature

World Neurosurg. 2016 Jun:90:700.e1-700.e5. doi: 10.1016/j.wneu.2016.02.031. Epub 2016 Feb 15.

Abstract

Background: Intracranial infectious aneurysms (IAs) are rare cerebrovascular lesions that represent only 1%-6% of all intracranial aneurysms. IAs are rare cerebrovascular lesions and pose a significant therapeutic challenge because of their angiographic and pathophysiologic features. We describe a patient with an intracranial IA treated by the use of reconstructive endovascular methods using a balloon-expandable covered stent and discuss the pathophysiologic characteristics of IA based on serial brain imaging findings.

Case description: A 21-year-old man was admitted to our emergency department with headache and vomiting. Neurologic examination, hematologic workup, and cerebrospinal fluid examination confirmed a diagnosis of bacterial meningitis. Initial brain magnetic resonance angiography revealed no significant stenosis lesions or aneurysm. After 4 weeks of antibiotic treatment, follow-up brain magnetic resonance imaging revealed an 8-mm sized aneurysm on the petrous portion of the right internal carotid artery, and 3 months later, follow-up brain magnetic resonance angiography revealed that the aneurysm had increased in size from 8 to 15 mm. Conventional 4-vessel angiography confirmed the presence of a pseudoaneurysm. Endovascular treatment was then planned via the use of a balloon-expandable covered stent. Postoperatively, the patient was discharged without specific neurologic deficit.

Conclusions: IAs are rare cerebrovascular lesions and pose a significant therapeutic challenge because of their angiographic and pathophysiologic features. Although endovascular treatment is not performed routinely for infectious aneurysms, the covered stent may represent a safe and effective treatment that achieves complete endoluminal reconstruction of the damaged vessel wall.

Keywords: Endovascular treatment; Infectious aneurysm; Mycotic aneurysm; Stent graft.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aneurysm, Infected / diagnostic imaging
  • Aneurysm, Infected / microbiology
  • Aneurysm, Infected / surgery*
  • Endovascular Procedures / instrumentation
  • Endovascular Procedures / methods*
  • Humans
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / microbiology
  • Intracranial Aneurysm / surgery*
  • Klebsiella Infections / diagnostic imaging
  • Klebsiella Infections / microbiology
  • Klebsiella Infections / surgery*
  • Male
  • Meningitis, Bacterial / diagnostic imaging
  • Meningitis, Bacterial / microbiology
  • Meningitis, Bacterial / surgery*
  • Plastic Surgery Procedures / instrumentation
  • Plastic Surgery Procedures / methods*
  • Stents
  • Treatment Outcome
  • Young Adult