Diffusion-weighted imaging outside the brain: Consensus statement from an ISMRM-sponsored workshop

Bachir Taouli; Ambros J Beer; Thomas Chenevert; David Collins; Constance Lehman; Celso Matos; Anwar R Padhani; Andrew B Rosenkrantz; Amita Shukla-Dave; Eric Sigmund; Lawrence Tanenbaum; Harriet Thoeny; Isabelle Thomassin-Naggara; Sebastiano Barbieri; Idoia Corcuera-Solano; Matthew Orton; Savannah C Partridge; Dow-Mu Koh

doi:10.1002/jmri.25196

Diffusion-weighted imaging outside the brain: Consensus statement from an ISMRM-sponsored workshop

J Magn Reson Imaging. 2016 Sep;44(3):521-40. doi: 10.1002/jmri.25196. Epub 2016 Feb 19.

Authors

Bachir Taouli¹, Ambros J Beer², Thomas Chenevert³, David Collins⁴, Constance Lehman⁵, Celso Matos⁶, Anwar R Padhani⁷, Andrew B Rosenkrantz⁸, Amita Shukla-Dave⁹, Eric Sigmund¹⁰, Lawrence Tanenbaum¹¹, Harriet Thoeny¹², Isabelle Thomassin-Naggara¹³, Sebastiano Barbieri¹², Idoia Corcuera-Solano¹, Matthew Orton⁴, Savannah C Partridge¹⁴, Dow-Mu Koh¹⁵

Affiliations

¹ Department of Radiology and Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
² Department of Nuclear Medicine, University Hospital Ulm, Ulm, Germany.
³ Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
⁴ CR UK Cancer Imaging Centre, Institute of Cancer Research and Department of Radiology, Royal Marsden Hospital, London, UK.
⁵ Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA.
⁶ Department of Radiology, Champalimaud Clinical Centre, Lisbon, Portugal.
⁷ Mount Vernon Cancer Centre, Northwood, UK.
⁸ Department of Radiology, NYU Langone Medical Center, New York, New York, USA.
⁹ Departments of Medical Physics and Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
¹⁰ Irene and Bernard Schwartz Center for Biomedical Imaging (CBI) and Center for Advanced Imaging and Innovation (CAI2R), Department of Radiology, NYU Langone Medical Center, New York, New York, USA.
¹¹ Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
¹² Department of Diagnostic Radiology, Inselspital Bern, Bern, Switzerland.
¹³ Université Pierre et Marie Curie, Hôpitaux Universitaires Paris-Est, Paris, France.
¹⁴ Department of Radiology, University of Washington, Seattle, USA.
¹⁵ Institute of Cancer Research and Department of Radiology, Royal Marsden Hospital, London, UK.

Abstract

The significant advances in magnetic resonance imaging (MRI) hardware and software, sequence design, and postprocessing methods have made diffusion-weighted imaging (DWI) an important part of body MRI protocols and have fueled extensive research on quantitative diffusion outside the brain, particularly in the oncologic setting. In this review, we summarize the most up-to-date information on DWI acquisition and clinical applications outside the brain, as discussed in an ISMRM-sponsored symposium held in April 2015. We first introduce recent advances in acquisition, processing, and quality control; then review scientific evidence in major organ systems; and finally describe future directions. J. Magn. Reson. Imaging 2016;44:521-540.

Keywords: breast; cancer; diffusion; kidney; liver; prostate; whole body imaging.

Publication types

Review

MeSH terms

Algorithms*
Brain / anatomy & histology
Brain / diagnostic imaging
Diffusion Magnetic Resonance Imaging / standards*
Humans
Image Enhancement / methods
Image Enhancement / standards*
Image Interpretation, Computer-Assisted / standards*
Imaging, Three-Dimensional / standards
Practice Guidelines as Topic*
Radiology / standards*
Reproducibility of Results
Sensitivity and Specificity

Abstract

Publication types

MeSH terms

Grants and funding