Is effective a prior multiparametric magnetic resonance scan in patients candidates to prostate biopsy? CAT Study

Abstract

We carried out a critically appraised topic (CAT)-type study to determine whether the relevant scientific evidence supports the recommendation of doing a multiparametric magnetic resonance imaging study of the prostate in all patients who are candidates for prostate biopsy with the aim of improving the detection of clinically significant prostate cancer and stratifying patients to receive active surveillance or treatment. After a formal literature search and an analysis of the two most relevant articles it found, we reached the conclusion that, despite promising results that point to the potential usefulness of this approach, there is still not enough clear scientific evidence to endorse it categorically. Before this approach can be endorsed, we need evidence from well-designed prospective randomized trials using widely agreed upon criteria and including large numbers of patients at multiple centers.

Keywords: Biopsia prostática; Especificidad; Multiparametric magnetic resonance imaging of the prostate; Neoplasia prostática; Prostate biopsy; Prostate neoplasm; Resonancia magnética multiparamétrica de próstata; Sensibilidad; Sensitivity; Specificity.