Chilling without regrets: Deciphering the effects of cryopreservation on the epigenetic properties of frozen cells will benefit the applications of cryo-technology

Anamika Chatterjee; Debapriya Saha; Birgit Glasmacher; Nicola Hofmann

doi:10.15252/embr.201642069

Chilling without regrets: Deciphering the effects of cryopreservation on the epigenetic properties of frozen cells will benefit the applications of cryo-technology

EMBO Rep. 2016 Mar;17(3):292-5. doi: 10.15252/embr.201642069. Epub 2016 Feb 11.

Authors

Anamika Chatterjee¹, Debapriya Saha¹, Birgit Glasmacher¹, Nicola Hofmann¹

Affiliation

¹ Institute for Multiphase Processes Leibniz Universität Hannover, Hanover, Germany.

Abstract

Cryopreservation is used widely in medicine and research to store cells and tissues. Surprisingly, the nature and impact of epigenetic changes that result from freezing is not well studied. Research into these changes is urgent to improve the safety and efficacy of cryopreservation for medical applications.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cryopreservation / methods*
Epigenesis, Genetic*
Humans
Tissue Preservation / methods*