Additive Effects on Asymmetric Catalysis

Liang Hong; Wangsheng Sun; Dongxu Yang; Guofeng Li; Rui Wang

doi:10.1021/acs.chemrev.5b00676

Additive Effects on Asymmetric Catalysis

Chem Rev. 2016 Mar 23;116(6):4006-123. doi: 10.1021/acs.chemrev.5b00676. Epub 2016 Feb 16.

Authors

Liang Hong¹, Wangsheng Sun², Dongxu Yang², Guofeng Li², Rui Wang^{1

2}

Affiliations

¹ School of Pharmaceutical Sciences, Sun Yat-sen University , Guangzhou, 510006 China.
² Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Lanzhou University , Lanzhou, 730000 China.

PMID: 26881289
DOI: 10.1021/acs.chemrev.5b00676

Abstract

This review highlights a number of additives that can be used to make asymmetric reactions perfect. Without changing other reaction conditions, simply adding additives can lead to improved asymmetric catalysis, such as reduced reaction time, improved yield, or/and increased selectivity.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Catalysis*
Chemistry Techniques, Synthetic / methods*
Isomerism