Has a mixture of amino acids and micronutrients influence on glucose metabolism and dietary fatty acid pattern in chronic psychosocially stressed persons? A pilot study

Int J Food Sci Nutr. 2016;67(2):195-202. doi: 10.3109/09637486.2016.1144718. Epub 2016 Feb 15.

Abstract

Brain food, e.g. L-tryptophan, antioxidative substances, B vitamins and magnesium are thought to be beneficial for obesity, inflammation and insulin resistance. In the present pilot study we hypothesised that a specific amino acid mixture with micronutrients improves the cardiometabolic situation of chronically stressed persons. Cardiovascular and metabolic parameters were analysed as per protocol in 32 patients. Chronic stress disorders in the same patients were assessed by a psychological neurological questionnaire (PNF). After dietary intervention a reduction of the fasting serum insulin concentrations occurred in the treatment group. An association was found between PNF values, insulin concentrations at baseline and an insulin reduction after 12 weeks. The results support the use of our specific dietary supplement for improved stress management and a decrease in metabolic dysfunction.

Keywords: Brain food; dietary supplement; insulin resistance; n-3 fatty acids; stress management; sympathetic nervous system.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Amino Acids / pharmacology*
  • Blood Glucose
  • Cardiovascular Diseases
  • Dietary Fats / metabolism*
  • Dietary Supplements*
  • Fatty Acids
  • Female
  • Glucose / metabolism*
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Risk Factors
  • Stress, Psychological*
  • Young Adult

Substances

  • Amino Acids
  • Blood Glucose
  • Dietary Fats
  • Fatty Acids
  • Glucose