HLA-DRB1, -DQA1 and -DQB1 genotyping of 180 Czech individuals from the Czech Republic pop 3

Marta Zajacova; Anna Kotrbova-Kozak; Marie Cerna

doi:10.1016/j.humimm.2016.02.003

HLA-DRB1, -DQA1 and -DQB1 genotyping of 180 Czech individuals from the Czech Republic pop 3

Hum Immunol. 2016 Apr;77(4):365-6. doi: 10.1016/j.humimm.2016.02.003. Epub 2016 Feb 8.

Authors

Marta Zajacova¹, Anna Kotrbova-Kozak¹, Marie Cerna²

Affiliations

¹ Dept. of General Biology and Genetics, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
² Dept. of General Biology and Genetics, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic. Electronic address: marie.cerna@lf3.cuni.cz.

PMID: 26867812
DOI: 10.1016/j.humimm.2016.02.003

Abstract

One hundred and eighty Czech individuals from the Czech Republic pop 3 were genotyped at the HLA-DRB1, -DQA1 and -DQB1 loci using sequence-specific primers PCR methods. HLA-DRB1, -DQA1 and -DQB1 genotypes are consistent with expected Hardy-Weinberg (HW) proportions. These genotype data are available in the Allele Frequencies Net Database under identifier AFND.

Keywords: Czech population; DQA1; DQB1; DRB1; HLA alleles.

MeSH terms

Alleles
Czech Republic
Gene Frequency
Genetics, Population*
Genotype*
HLA-DQ alpha-Chains / genetics*
HLA-DQ beta-Chains / genetics*
HLA-DRB1 Chains / genetics*
Haplotypes
Humans

Substances

HLA-DQ alpha-Chains
HLA-DQ beta-Chains
HLA-DRB1 Chains