The 'pit-crew' model for improving door-to-needle times in endovascular stroke therapy: a Six-Sigma project

J Neurointerv Surg. 2016 May;8(5):447-52. doi: 10.1136/neurintsurg-2015-012219. Epub 2016 Jan 11.

Abstract

Background: Delays in delivering endovascular stroke therapy adversely affect outcomes. Time-sensitive treatments such as stroke interventions benefit from methodically developed protocols. Clearly defined roles in these protocols allow for parallel processing of tasks, resulting in consistent delivery of care.

Objective: To present the outcomes of a quality-improvement (QI) process directed at reducing stroke treatment times in a tertiary level academic medical center.

Methods: A Six-Sigma-based QI process was developed over a 3-month period. After an initial analysis, procedures were implemented and fine-tuned to identify and address rate-limiting steps in the endovascular care pathway. Prospectively recorded treatment times were then compared in two groups of patients who were treated 'before' (n=64) or 'after' (n=30) the QI process. Three time intervals were measured: emergency room (ER) to arrival for CT scan (ER-CT), CT scan to interventional laboratory arrival (CT-Lab), and interventional laboratory arrival to groin puncture (Lab-puncture).

Results: The ER-CT time was 40 (±29) min in the 'before' and 26 (±15) min in the 'after' group (p=0.008). The CT-Lab time was 87 (±47) min in the 'before' and 51 (±33) min in the 'after' group (p=0.0002). The Lab-puncture time was 24 (±11) min in the 'before' and 15 (±4) min in the 'after' group (p<0.0001). The overall ER-arrival to groin-puncture time was reduced from 2 h, 31 min (±51) min in the 'before' to 1 h, 33 min (±37) min in the 'after' group, (p<0.0001). The improved times were seen for both working hours and off-hours interventions.

Conclusions: A protocol-driven process can significantly improve efficiency of care in time-sensitive stroke interventions.

Keywords: Standards; Stroke.

MeSH terms

  • Academic Medical Centers / standards
  • Aged
  • Aged, 80 and over
  • Emergency Medical Services / methods*
  • Emergency Medical Services / standards
  • Endovascular Procedures / methods*
  • Endovascular Procedures / standards
  • Female
  • Humans
  • Male
  • Middle Aged
  • Needles*
  • Stroke / diagnostic imaging*
  • Stroke / therapy*
  • Thrombolytic Therapy / methods*
  • Thrombolytic Therapy / standards
  • Time Factors
  • Time-to-Treatment* / standards
  • Tissue Plasminogen Activator / administration & dosage
  • Tomography, X-Ray Computed / methods
  • Tomography, X-Ray Computed / standards

Substances

  • Tissue Plasminogen Activator