CD3(+)/CD45(+) and SMA-α(+) circulating microparticles are increased in individuals at high cardiovascular risk who will develop a major cardiovascular event

Gemma Chiva-Blanch; Rosa Suades; Javier Crespo; Gemma Vilahur; Gemma Arderiu; Teresa Padró; Dolores Corella; Jordi Salas-Salvadó; Fernando Arós; Miguel-Angel Martínez-González; Emilio Ros; Montse Fitó; Ramon Estruch; Lina Badimon

doi:10.1016/j.ijcard.2016.01.211

CD3(+)/CD45(+) and SMA-α(+) circulating microparticles are increased in individuals at high cardiovascular risk who will develop a major cardiovascular event

Int J Cardiol. 2016 Apr 1:208:147-9. doi: 10.1016/j.ijcard.2016.01.211. Epub 2016 Jan 28.

Affiliations

¹ Cardiovascular Research Center (CSIC-ICCC), Barcelona, Spain; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain.
² CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Department of Preventive Medicine and Public Health, University of Valencia, Valencia, Spain.
³ CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Human Nutrition Unit, Hospital Universitari Sant Joan, Institut d'Investigacions Sanitàries Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.
⁴ CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Department of Cardiology, University Hospital Araba, Vitoria, Spain.
⁵ CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Department of Epidemiology and Public Health, University of Navarra, Pamplona, Spain.
⁶ CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Lipid Clinic, Endocrinology and Nutrition Service, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, Spain.
⁷ CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Cardiovascular Risk and Nutrition Research Group (Regicor Study Group), Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, Spain.
⁸ CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Spain.
⁹ Cardiovascular Research Center (CSIC-ICCC), Barcelona, Spain; Biomedical Research Institute Sant Pau (IIB-Sant Pau), Barcelona, Spain. Electronic address: lbadimon@csic-iccc.org.

PMID: 26859321
DOI: 10.1016/j.ijcard.2016.01.211

No abstract available

Keywords: CD3; Cardiovascular disease; Circulating microparticles; Framingham risk score; Lymphocytes; Smooth muscle cells.

Publication types

Letter
Multicenter Study
Randomized Controlled Trial

MeSH terms

Biomarkers / blood
CD3 Complex / blood*
Cardiovascular Diseases / blood*
Cardiovascular Diseases / diagnosis*
Cardiovascular Diseases / prevention & control
Case-Control Studies
Cell-Derived Microparticles / metabolism*
Diet, Mediterranean
Follow-Up Studies
Humans
Leukocyte Common Antigens / blood*
Myocytes, Smooth Muscle / metabolism*
Prospective Studies
Risk Factors

Substances

Biomarkers
CD3 Complex
Leukocyte Common Antigens
PTPRC protein, human