Fusion FDG-PET/MRI Evidence to Support Diagnosis of Frontotemporal Dementia-Related Primary Progressive Aphasia

Clin Nucl Med. 2016 Sep;41(9):e422-3. doi: 10.1097/RLU.0000000000001175.

Abstract

A 61-year-old right-handed man presented for cognitive neurological evaluation with word-finding difficulty, impaired word retrieval, impaired repetition of phrases, and stammering. Brain MRI and FDG-PET/CT were performed as initial imaging workup. Further FDG PET/MRI brain images were obtained through software fusion and revealed regional cortical atrophy with corresponding hypometabolic activity involving the posterior aspects of the left middle and inferior temporal gyri. These characteristic imaging findings are supportive of patient's diagnosis of frontotemporal dementia-related primary progressive aphasia.

Publication types

  • Case Reports

MeSH terms

  • Aphasia, Primary Progressive / diagnostic imaging*
  • Aphasia, Primary Progressive / etiology
  • Atrophy
  • Fluorodeoxyglucose F18
  • Frontotemporal Dementia / complications
  • Frontotemporal Dementia / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Multimodal Imaging
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Temporal Lobe / diagnostic imaging*
  • Temporal Lobe / pathology

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18