Nonparametric restricted mean analysis across multiple follow-up intervals

Nabihah Tayob; Susan Murray

doi:10.1016/j.spl.2015.11.014

Nonparametric restricted mean analysis across multiple follow-up intervals

Stat Probab Lett. 2016 Feb 1:109:152-158. doi: 10.1016/j.spl.2015.11.014.

Authors

Nabihah Tayob¹, Susan Murray²

Affiliations

¹ The University of Texas MD Anderson Cancer Center, Department of Biostatistics, 1400 Pressler St, Houston, TX 77030, U.S.A.
² University of Michigan, Department of Biostatistics, Ann Arbor, Michigan 48109, U.S.A.

Abstract

We provide a nonparametric estimate of τ-restricted mean survival using follow-up information beyond τwhen appropriate to improve precision. The variance accounts for correlation between follow-up windows. Both asymptotic calculations and simulation studies recommend follow-up intervals spaced approximately τ/2 apart.

Keywords: Correlated times-to-events; Follow-up intervals; Residual life; Restricted mean survival.

Abstract

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