Identification of five substituted phenethylamine derivatives 5-MAPDB, 5-AEDB, MDMA methylene homolog, 6-Br-MDMA, and 5-APB-NBOMe

Drug Test Anal. 2017 Feb;9(2):199-207. doi: 10.1002/dta.1955. Epub 2016 Feb 9.

Abstract

This paper reports analytical properties of five substituted phenethylamine derivatives seized from a clandestine laboratory. These five derivatives include 5-(2-methylaminopropyl)-2,3-dihydrobenzofuran (5-MAPDB, 1), 5-(2-aminoethyl)-2,3-dihydrobenzofuran (5-AEDB, 2), N,2-dimethyl-3-(3,4-methylenedioxyphenyl)propan-1-amine (MDMA methylene homolog, 3), 6-bromo-3,4-methylenedioxymethamphetamine (6-Br-MDMA, 4), and 1-(benzofuran-5-yl)-N-(2-methoxybenzyl)propan-2-amine (5-APB-NBOMe, 5). These compounds were identified by liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF-MS), gas chromatography-mass spectrometry (GC-MS), and nuclear magnetic resonance spectroscopy (NMR). No analytical properties about compounds 1-4 have appeared until now, making this the first report on these compounds. Copyright © 2016 John Wiley & Sons, Ltd.

Keywords: 5-AEDB; 5-APB-NBOMe; 5-MAPDB; 6-Br-MDMA; MDMA methylene homolog; new psychoactive substance; substituted phenethylamine derivatives.

MeSH terms

  • Designer Drugs / analysis*
  • Gas Chromatography-Mass Spectrometry
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • N-Methyl-3,4-methylenedioxyamphetamine / analogs & derivatives
  • Phenethylamines / analysis*
  • Psychotropic Drugs / analysis*

Substances

  • Designer Drugs
  • Phenethylamines
  • Psychotropic Drugs
  • phenethylamine
  • N-Methyl-3,4-methylenedioxyamphetamine