Carbohydrate-Catalyzed Enantioselective Alkene Diboration: Enhanced Reactivity of 1,2-Bonded Diboron Complexes

Lichao Fang; Lu Yan; Fredrik Haeffner; James P Morken

doi:10.1021/jacs.5b13174

Carbohydrate-Catalyzed Enantioselective Alkene Diboration: Enhanced Reactivity of 1,2-Bonded Diboron Complexes

J Am Chem Soc. 2016 Mar 2;138(8):2508-11. doi: 10.1021/jacs.5b13174. Epub 2016 Feb 16.

Authors

Lichao Fang¹, Lu Yan¹, Fredrik Haeffner¹, James P Morken¹

Affiliation

¹ Department of Chemistry, Merkert Chemistry Center, Boston College , Chestnut Hill, Massachusetts 02467, United States.

Abstract

Catalytic enantioselective diboration of alkenes is accomplished with readily available carbohydrate-derived catalysts. Mechanistic experiments suggest the intermediacy of 1,2-bonded diboronates.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Alkenes / chemistry*
Boron Compounds / chemical synthesis
Boron Compounds / chemistry*
Catalysis
Glycols / chemistry*
Stereoisomerism

Substances

Alkenes
Boron Compounds
Glycols

Abstract

Publication types

MeSH terms

Substances

Grants and funding