Chip-Scale Fabrication of High-Q All-Glass Toroidal Microresonators for Single-Particle Label-Free Imaging

Adv Mater. 2016 Apr 20;28(15):2945-50. doi: 10.1002/adma.201504976. Epub 2016 Feb 8.

Abstract

Whispering-gallery-mode microresonators enable materials for single-molecule label-free detection and imaging because of their high sensitivity to their micro-environment. However, fabrication and materials challenges prevent scalability and limit functionality. All-glass on-chip microresonators significantly reduce these difficulties. Construction of all-glass toroidal microresonators with high quality factor and low mode volume is reported and these are used as platforms for label-free single-particle imaging.

Keywords: label-free imaging; label-free sensing; optical microcavities; optical microresonators; single-particle sensing.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Equipment Design
  • Glass*
  • Microtechnology / instrumentation*
  • Temperature