Margins for cervical and vulvar cancer

J Surg Oncol. 2016 Mar;113(3):304-9. doi: 10.1002/jso.24108. Epub 2016 Feb 8.

Abstract

Surgery is the primary treatment for vulvar cancer as well as early-stage carcinoma of the cervix. This article reviews the significance of margin status after surgery on overall survival, need for further surgical intervention, and role for possible adjuvant therapy. It summarizes the abundant literature on margin status in vulvar cancer and highlights the need for further investigation on the prognostic significance of margins in cervical cancer. In addition, it reviews other important operative considerations.

Keywords: cervical neoplasms; vulvar neoplasms.

Publication types

  • Review

MeSH terms

  • Chemotherapy, Adjuvant
  • Disease-Free Survival
  • Electrosurgery
  • Female
  • Fertility Preservation
  • Frozen Sections
  • Humans
  • Hysterectomy / methods*
  • Hysterectomy / standards*
  • Intraoperative Period
  • Neoplasm Recurrence, Local / prevention & control*
  • Neoplasm Staging
  • Neoplasm, Residual / prevention & control
  • Organ Sparing Treatments / methods
  • Organ Sparing Treatments / standards
  • Predictive Value of Tests
  • Prognosis
  • Radiotherapy, Adjuvant
  • Survival Rate
  • Trachelectomy / standards
  • United States / epidemiology
  • Uterine Cervical Neoplasms / epidemiology
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / prevention & control*
  • Uterine Cervical Neoplasms / surgery*
  • Vulvar Neoplasms / epidemiology
  • Vulvar Neoplasms / pathology
  • Vulvar Neoplasms / prevention & control*
  • Vulvar Neoplasms / surgery*