The Matrix Metalloproteinase 9 Point-of-Care Test in Dry Eye

Ocul Surf. 2016 Apr;14(2):189-95. doi: 10.1016/j.jtos.2015.10.004. Epub 2016 Feb 2.

Abstract

Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. However, the subjective symptoms of dry eye poorly correlate to the current gold standard for diagnostic tests, reflecting the need to develop better objective tests for the diagnosis of dry eye. This review considers the role of ocular surface matrix metalloproteinase 9 (MMP-9) in dry eye and the implications of a novel point-of-care test that measures MMP-9 levels, InflammaDry (RPS, Sarasota, FL) on choosing appropriate therapeutic treatments.

Keywords: InflammaDry; dry eye; matrix metalloproteinase 9.

Publication types

  • Review

MeSH terms

  • Dry Eye Syndromes*
  • Eye
  • Humans
  • Keratoconjunctivitis Sicca
  • Matrix Metalloproteinase 9
  • Point-of-Care Systems

Substances

  • Matrix Metalloproteinase 9