[Influencing factors on AIDS-related deaths in Guangzhou 1991-2013]

Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Dec;36(12):1406-9.
[Article in Chinese]

Abstract

Objective: To analyze the influencing factors on AIDS-related deaths among HIV/AIDS patients in Guangzhou, Guangdong province.

Methods: A retrospective cohort was formed, based on available data of HIV/AIDS patients between 1991 and 2013 in Guangzhou, that were gathered from the Chinese AIDS Prevention and Control Information System. Cox proportional hazard model was used to identify the influencing factors for AIDS-related deaths.

Results: Data showed that factors as: existence of full-bloom AIDS when HIV infection was diagnosed (HR =2.717, 95%CI: 2.039-3.621) , diagnose of AIDS was made in the hospitals (HR=1.516, 95%CI: 1.159-1.981) , never received no CD(4) count testing (HR=4.866, 95%CI: 3.674-6.444) , no drugs were provided to those who met the criteria for treatment (HR=12.213, 95%CI: 8.467-17.616) , and patients at aged ≥40 years when HIV infection was diagnosed etc., were related to the risk for AIDS deaths. The risk of AIDS-related death was also high in those who did not meet the treatment criteria or receiving no treatment, when compared to those who had received the antiviral treatment (HR=1.936, 95%CI: 1.145-3.272).

Conclusion: Factors as: earlier diagnosis of HIV/AIDS cases, provision of CD(4) count testing and antiviral treatment to more cases etc, could decrease the risk for AIDS-related deaths and improve the survival rate on HIV/AIDS cases.

MeSH terms

  • Acquired Immunodeficiency Syndrome / diagnosis
  • Acquired Immunodeficiency Syndrome / drug therapy
  • Acquired Immunodeficiency Syndrome / mortality*
  • Adult
  • Antiviral Agents / therapeutic use
  • CD4 Lymphocyte Count / statistics & numerical data
  • China / epidemiology
  • Early Diagnosis
  • HIV Infections / diagnosis
  • Humans
  • Proportional Hazards Models
  • Retrospective Studies
  • Risk Factors
  • Survival Rate

Substances

  • Antiviral Agents